Stating that synephrine is known to cause heart damage and that caffeine “enhances” the effects of synephrine—an ephedrine-like substance found naturally in the peels of citrus fruit—the Finnish Food Safety Authority (EVIRA ) has asked for all fat-burning food supplements containing the ingredients to be withdrawn from the market. “Doubts have been voiced about the safety of food supplements containing synephrine and caffeine,” said EVIRA . “Based on the risk assessments they have carried out, Denmark and Sweden have declared food supplements containing synephrine and caffeine in a combination to be unsafe to health and they may therefore not be marketed.”