In May 2016, the U.S. Food and Drug Administration (FDA) issued revisions to its Bacteriological Analytical Manual, Chapter 23, Microbiological Methods for Cosmetics. The modifications address dilution rates, screening tests for total numbers of microorganisms and identification of microbes. Among the subjects addressed methods for isolating micro-organisms from cosmetic products, the equipment and materials needed for isolation and identification, and handling and testing of samples.