The European Commission has decided not to raise any objections under the EC Treaty state aid rules to the financial support of €46.3 million granted by France to the BioIntelligence research and development programme. The programme, to be coordinated by Dassault Systèmes, will involve SMEs specialised in bioinformatics, life science industries and public research institutes. BioIntelligence will promote the use of systemic modelling and simulation tools to exploit biomedical databases. This innovative approach, based on the Product Lifecycle Management method used by manufacturing industries, will enable life science industries to optimise their research phases. The Commission concluded that the programme was compatible with the EU R&D framework. In particular, the programme addresses a market failure and looks set to create positive effects in all bioinformatic and public health sectors without significantly changing competition conditions.