The U.S. Environmental Protection Agency (EPA) has released a guidance document that consolidates information on the criteria for waiving and bridging acute toxicity testing requirements that have previously appeared in numerous separate documents, including pesticide registration notices, Office of Chemical Safety and Pollution Prevention guidance and Office of Pesticide Programs memoranda. The new guidance outlines the requirements for obtaining waivers for several kinds of animal testing, including acute oral toxicity, acute dermal toxicity and acute inhalation toxicity studies. According to EPA, the guidance is intended to “provide a single source for consultation on the use of waiver and bridging criteria for acute toxicity testing” to reduce confusion for pesticide registrants.