The National Nanotechnology Initiative (NNI ) has released an updated strategy intended “to ensure the responsible development of nanotechnology by providing guidance to Federal agencies that produce scientific information for risk management, regulatory decision making, product use, research planning, and public outreach.” Consisting of representatives from more than 20 federal agencies, NNI was established in 2000 to coordinate goals, priorities and strategies with respect to the federal government’s nanotechnology research and development program. NNI has reportedly coordinated more than $12 billion in advancing its mission. Its updated strategy includes chapters on nanomaterial measurement infrastructure, human exposure assessment, human health, the environment, risk-assessment and risk-management methods, and informatics and modeling for nanotech research.