A recent study has concluded that “higher intake of folate is marginally associated with a lower risk for [estrogen receptor negative] ER- breast cancer, and higher intakes of vitamin B-12 and methionine [an amino acid] are marginally associated with a lower risk of ER+ breast cancer.” The study included 2,325 women from the 4-Corners Breast Cancer Study and also evaluated menopausal status, ethnicity and alcohol intake. Among other things, the study showed that (i) “women in the highest quartile of folate intake [] associated with 50 percent reduced risk for ER+ breast cancer compared with those in the lower quartile”; (ii) “those in the highest quartile of vitamin B12 intake were 27 percent less likely to develop breast cancer, compared with those in the lowest quartile”; and (iii) “among non-Hispanic women, the highest intake of vitamin B12 was associated with 51 percent reduced risk for breast cancer.”