According to the Bureau of Economic and Business Research of the University of Florida, the state resumed its pattern of population growth in 2010, a year after sustaining its first population decline since the 1940s.

The bureau announced on September 2, 2010, that Florida's population grew by 21,285 persons between April 1, 2009 and April 1, 2010. In the previous year, Florida population declined by 56,736 persons. Referring to the 2010 population increase, Stan Smith, director of the research bureau, said that “Even though the state turned it around, it still represents the smallest population increase since the 1940s and does not make up for last year's loss. Florida's population growth continues to be very, very slow by historical standards.” He noted that the state's population grew by more than 125,000 persons every year from 1950 through 2008, and by more than 300,000 a year from the 1970s through 2006.

As of April 1, 2010, Florida's estimated population was 18,771,768.