California’s Department of Toxic Substances Control (DTSC) launched its Safer Consumer Products green chemistry program in 2013. Under the program, the DTSC evaluates products for chemicals of concern, and based upon potential exposure to a chemical of concern might list a product as a priority product. The DTSC has prioritized products in the following categories: Beauty, Personal Care, and Hygiene Products; Cleaning Products; Household, School, and Workplace Furnishings and Décor; Building Products and Materials Used in Construction and Renovation; Consumable Office, School, and Business Supplies; Food Packaging; and Lead-Acid Batteries. Once a product is listed as a priority, manufacturers, importers and distributors are required to conduct a chemical alternatives analysis to evaluate whether a safer chemical can be substituted for the chemical of concern.

Effective July 1, 2018, spray polyurethane foam (SPF) systems with unreacted methylene diphenyl diisocyanates were listed as priority products. On August 9, 2019, the American Chemistry Council and an SPF manufacturer filed the first challenge to the Safer Consumer Products program, which seeks to force the DTSC to remove SPF systems as a listed priority product.