On May 20, 2009, Attorney General Eric H. Holder, Jr. and US Department of Health and Human Services Secretary Kathleen Sebelius announced the assignment of US Department of Justice (DOJ) Health Care Strike Forces to Detroit and Houston.

Covert Strike Force "Phase One" operations began in Miami-Dade County, Florida in March 2007. Federal and State agents included personnel from the FBI, HHS-OIG, the Florida Medicaid Fraud Control Unit and other local officials. The Strike Force's investigations in Miami-Dade have concentrated on HIV/AIDS infusion therapy and DME fraud.

Covert Strike Force "Phase Two" operation began in Los Angeles County, California in March 2008. The LA Strike Forces investigations have focused largely on DME fraud and health care testing facilities.

To date, the Health Care Strike Forces have filed criminal charges against 196 defendants, the majority of which have been resolved through guilty pleas.

The selection of Detroit and Houston was reportedly based on a review of Medicare claims data suggesting high levels of billing irregularities.

President Obama's 2010 budget plan would allocate $311 million for antifraud enforcement, including nearly $30 million for the DOJ. The omnibus appropriation for 2009 would give $19 million more to the DOJ for its strike force initiative this year.