On August 2, 2017, the Department of Energy (DOE) announced that a fourth project under the MEGA-BIO: Bioproducts to Enable Biofuels Funding Opportunity would be awarded up to $1.8 million. Michigan State University was selected to manage the fourth project, which will work in partnership with the University of Wisconsin–Madison and MBI International to optimize a two-stage process for deconstruction of biomass into two clean intermediate streams, specifically sugars for the production of hydrocarbon fuels and lignins for the production of multiple value-added chemicals.

In August 2016, DOE’s Bioenergy Technologies Office (BETO) selected three projects for an initial round of funding; the total funding for the four awards is $13.1 million. All four projects support the development of biomass-to-hydrocarbon biofuels conversion pathways that can produce variable amounts of fuels and/or products based on external factors allowing for the conversion of biomass where it is most impactful and a positive return on investment.