On May 26, 2009, the Federal Comparative Effectiveness Research Coordination Council announced that it is seeking comment on its draft definition of comparative effectiveness research and its draft prioritization criteria for comparative effectiveness research and investments. With regard to prioritization, the Council proposes to use the following criteria for determining “scientifically meritorious research and investments” potential impact (based on prevalence of condition, burden of disease, variability in outcomes, and costs of care); potential to evaluate comparative effectiveness in diverse populations and patient sub-populations; uncertainty within the clinical and public health communities regarding management decisions; addresses need or gap unlikely to be addressed through other funding mechanisms; and potential for multiplicative effect (e.g. lays foundation for future comparative effectiveness research or generates additional investment outside government). Comments are being accepted but no comment deadline is specified.