The European Food Safety Authority (EFSA) has concluded that the sweetener advantame is safe for human consumption. Derived from aspartame and vanillin, advantame is reportedly 37,000 times sweeter than sugar and 100 times sweeter than aspartame and can be used to enhance flavors such as fruit, citrus and mint and to extend the sweetness duration in chewing gum. The agency has established an acceptable daily intake of 5 mg per kilogram of bodyweight per day. See ajinomoto.com.