The Medicines and Healthcare products Regulatory Agency (MHRA) has put in place changes, effective from 21 December 2009, to medicines regulations to enable mixing of medicines prior to administration in clinical practice:

  • Doctors/dentists who can already mix medicines, can direct others to mix
  • Nurse and Pharmacist Independent Prescribers to mix themselves and direct others to do so
  • Supplementary Prescribers to mix themselves and direct others to do so, but only where that preparation forms part of Clinical Management Plan for an individual patient
  • Nurse and Pharmacist Independent Prescribers to prescribe unlicensed medicines for their patients, on same basis as doctors and dentists (and Supplementary Prescribers if part of Clinical Management Plan)

The changes define mixing as “the combination of two or more medicinal products together for the purposes of administering them to meet needs of a particular patient”.

Department of Health 7 January 2010