A safety review panel formed by the U.S. Army and Department of Defense (DOD) has issued a report which concludes that although DMAA (1,3-dimethlyamylamine) did not evidently cause the deaths of four soldiers who died with the ingredient in their bloodstreams, the substance still poses potential health risks and should remain banned from military stores. The report was released by DOD’s Human Performance Research Center and covers a twoyear study of DMAA that began in 2011 after the soldiers’ deaths.
The safety panel concluded that despite a high apparent usage of DMAA among service members (as high as 15 percent), the substance, at the manufacturer-recommended doses, poses a low risk of serious harm for most healthy service members. “The existing evidence does not conclusively establish that DMAA -containing substances are causally-associated with adverse medical events,” noted the report. “However, a consistent theme among the studies is that DMAA use potentially affects cardiovascular function, just as other sympathomimetic stimulants. Without further rigorous study designs developed to evaluate the safety of DMAA , especially in patients with concomitant use of other substances, co-morbid conditions and high frequency use, the magnitude of the association of DMAA with adverse medical events is uncertain.”
Most manufacturers and marketers of DMAA -containing products have either stopped producing such products or reformulated them to be DMAA -free after the Food and Drug Administration warned in 2012 that the substance was not legal in dietary supplements and was subject to a subsequent class action lawsuit. Additional details appear in Issues 5 and 7 of this Report. See NaturalProductsInsider, August 7, 2013.
Meanwhile, supplement manufacturer BPI Sports, LLC, has reportedly discontinued advertising claims for three of its products, one of which contains DMAA , after the claims were challenged by the Council for Responsible Nutrition. One of the products, Go Performance Pre-Training Powder, made the following claims: “Stronger than 13 DMAA ” and “Hits You Harder. Lasts Longer. Crazy Energy. Zero Crash.” Evidently, BPI Sports did not attempt to support the claims with evidence and instead pulled the claims from products and marketing materials and told the National Advertising Division that the company does not intend to make such claims in the future. See truthinadvertising.org, August 9, 2013.