On March 12, 2015, the FDA issued a recall for Zimmer Persona Trabecular Metal Tibial Plate / Persona TM Tibia-Prosthesis knee implants after patients complained of complications involving loosening of the knee joint and large gaps in between knee replacement components or between bone and the components, also known as radiolucent lines.

Some patients have complained of symptoms including: severe pain, swelling of the joint, loss of mobility, loss of bone, or knee replacement device failure. Patients may need corrective surgery to alleviate these symptoms and in some cases, the knee implant may have to be replaced.