South Alabama Medical Science Foundation, Merck & Cie, and Pamlab LLC filed a letter on September 10, 2012, requesting that the International Trade Commission conduct an investigation under section 337 covering Certain Reduced Folate Nutraceutical Products and L-Methylfolate Raw Ingredients Used Therein. The proposed respondents are: Gnosis Spa, Gnosis Bioresearch SA, Gnosis USA Inc., and Macoven Pharmaceuticals LLC.